Santa Ana is known for its rich tapestry of faith traditions, reflecting its diverse and vibrant community. Christian denominations like Baptist, Presbyterian, Methodist, Lutheran, Evangelical, Non‑Denominational, Pentecostal, and African‑American churches are well‑represented, offering a wide range of worship styles and community services. The Catholic presence is significant, with numerous parishes serving largely Hispanic congregations. Additionally, the city hosts Jewish Reform congregations, Buddhist and Hindu temples catering to its Asian population, as well as Latter‑day Saints meetinghouses.

These faith centers not only provide worship services but also anchor the community through language‑specific services, outreach programs, cultural events, and interfaith dialogue. Hispanic and Vietnamese residents, in particular, are supported by Spanish- and Vietnamese-language masses and temple rituals, while African‑American and Asian Pacific American Christians have churches that reflect their cultural heritages. The result is a spiritually diverse city where faith and culture intertwine.